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FPGEE NABP Foreign Pharmacy Graduate Equivalency Examination Free Practice Exam Questions (2025 Updated)

Prepare effectively for your NABP FPGEE Foreign Pharmacy Graduate Equivalency Examination certification with our extensive collection of free, high-quality practice questions. Each question is designed to mirror the actual exam format and objectives, complete with comprehensive answers and detailed explanations. Our materials are regularly updated for 2025, ensuring you have the most current resources to build confidence and succeed on your first attempt.

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Total 426 questions

Intal-Sodium cromoglycate is characterized by which of the following statements?

I- Non-steroidal drug with anti-inflammatory proprieties

II- They can be used in prophylaxis of asthma and allergic rhinitis

III Used in asthma only

A.

I only

B.

III only

C.

I and II only

D.

II and III only

E.

All are correct

Which of the following vitamins is depleted in the blood by smoke?

A.

Vitamin C

B.

Vitamin B

C.

Vitamin E

D.

Vitamin D

E.

Vitamin A

Goals of gout treatment may include:

I- Reduce inflammation during acute attacks

II- Accelerate renal excretion of uric acid

III- Reduce the conversion of purine to uric acid

A.

I only

B.

III only

C.

I and II only

D.

II and III only

E.

All are correct

Mechanisms of drug interactions with acetylsalicylic acid (ASA. include:

A.

induction of microsomal enzymes

B.

inhibition of microsomal enzymes

C.

inhibition of liposomal enzymes

D.

displacement of other drugs bound to serum albumin

E.

enhanced platelet aggregation

Drug that inhibits xanthine oxidase and affect the metabolism of 6-mercaptopurine:

A.

Sulfinpyrazone

B.

Allopurinol

C.

Penicillamine

D.

Purinethol

E.

Celecoxib

Advantages of nasal route over oral route absorption of drugs may include:

I- Nasal route has a higher surface area

II- Nasal route has more blood vessels

III- Nasal route has a higher onset of absorption

A.

I only

B.

III only

C.

I and II only

D.

II and III only

E.

All are correct

In some parenteral formulations, sodium metabisulphite is included as:

A.

an antioxidant

B.

a chelator

C.

a solubilizer

D.

a cosolvent

E.

an emulsifier

In the treatment of rheumatoid arthritis, the salicylates:

A.

Stop and often reverse the progressive joint involvement.

B.

Specifically reverse the cause of the disease.

C.

Provide only analgesic and anti-inflammatory effects.

D.

Are effective because they are uricosuric agents.

E.

Are more effective when given with allopurinol.

All are examples of drugs used in the treatment of bronchoconstriction, EXCEPT:

A.

β2-agonists

B.

Anticholinergic

C.

Methyl xanthenes

D.

Xanthine oxidase inhibitors

E.

Leukotriene modifiers

All of the following drugs will increase the heart rate directly or by reflex when injected intravenously into a young healthy adult, EXCEPT:

A.

isoproterenol

B.

histamine

C.

phentolamine

D.

phenylephrine

E.

atropine

Which is the correct start dose of methothrexate in the treatment of rheumatoid arthritis?

A.

7.5mg once a week

B.

15mg once a week

C.

7.5mg daily

D.

15mg daily

E.

22mg once a week

Which of the following agents is the best choice of treatment for an asthma patient with rheumatoid arthritis who is considered to have aspirin sensitivity?

A.

Ibuprofen

B.

Acetaminophen

C.

Gold therapy

D.

Azathioprine

E.

Cyclophosphamide

Which of the hydroxyls in the compound above is a tertiary alcohol?

A.

Hydroxyl 1

B.

Hydroxyl 2

C.

Hydroxyl 3

D.

Hydroxyl 4

E.

Hydroxyls 1 and 2

Which of the following antacids has cathartic side-effects?

A.

Calcium carbonate

B.

Dihydroxyaluminum sodium carbonate

C.

Magnesium hydroxide

D.

Calcium sulfate

E.

Aluminum silicate

Organisms commonly implicated in the cause of Traveller's Diarrhea include:

I Bacteroides fragilis

II Escherichia coli

III Shigella sp

A.

I only

B.

III only

C.

I and II only

D.

II and III only

E.

I, II and III

Drugs shown to be effective in the prevention of Travellers'

Diarrhea, which might have been prescribed for SM include:

I doxycycline

II cotrimoxazole

III amoxicillin

A.

I only

B.

III only

C.

I and II only

D.

II and III only

E.

I, II and III

Uricosuric agents are used in gout treatment by inhibiting the uric acid re-absorption in the proximal tubules, the best example of

a uricosuric agent is:

A.

Allopurinol

B.

sulphinpyrazone

C.

Indomethacin

D.

Penicillamine

E.

Methotrexate

Chronic progressive lower airway destruction causing reduced pulmonary inspiration and expiratory capacity is known as:

A.

Asthma

B.

Bronchitis

C.

GERD

D.

COPD

E.

CHF

The above structures are related to one another as:

A.

bioisosteres

B.

enantiomers

C.

homologs

D.

rotamers

E.

positional (structural) isomers

If the total body clearance of a drug is 200 mL/min in a normal healthy adult and the renal clearance is 10 mL/min then one may assume that:

A.

the drug is extensively metabolized.

B.

greater than normal drug accumulation would occur in patients with moderate renal failure.

C.

entero-hepatic recycling is significant.

D.

the drug is not bound to plasma proteins.

E.

the drug is concentrated in adipose tissue.

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Total 426 questions
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