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MCCQE Medical Council of Canada MCCQE Part 1 Exam Free Practice Exam Questions (2025 Updated)

Prepare effectively for your Medical Council of Canada MCCQE MCCQE Part 1 Exam certification with our extensive collection of free, high-quality practice questions. Each question is designed to mirror the actual exam format and objectives, complete with comprehensive answers and detailed explanations. Our materials are regularly updated for 2025, ensuring you have the most current resources to build confidence and succeed on your first attempt.

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Total 230 questions

An 80-year-old woman presents to your office with weight loss and generalized weakness. Her husband calls you after the appointment and asks that his wife not be told if she is diagnosed with cancer as hearing this will likely "kill her." Investigations subsequently show that she has metastatic lung cancer. Which one of the following is the best next step?

A.

Telephone her to inform her she has a bad pneumonia and prescribe antibiotics.

B.

Tell her husband she has metastatic lung cancer.

C.

Book an immediate appointment with your patient.

D.

Tell the patient she requires a computed tomography scan of the chest.

E.

Arrange an urgent consultation with her children to confirm her wishes.

A 70-year-old woman had a total abdominal hysterectomy with bilateral salpingo-oophorectomy 2 days ago. On examination today, her vital signs are as follows: She has been immobile since her operation. She is fatigued but is tolerating a full diet. Which one of the following is the most likely cause of this patient's fever?

A.

Septic pelvic thrombophlebitis.

B.

Pulmonary embolism.

C.

Wound infection.

D.

Bowel trauma during the operation.

E.

Atelectasis

A 21-year-old man presents to the Emergency Department with a 6-month history of unusual behavior. He believes that he has been specially chosen to found a new religion. He says he has seen visions of angels in his bedroom. He appears disheveled and malodorous. On further inspection, you note that he drinks 2 liters daily. Which one of the following is the most appropriate initial management?

A.

Electroconvulsive therapy

B.

Risperidone

C.

Valproic acid

D.

Carbamazepine

E.

Cognitive behavior therapy

You are caring for a 78-year-old man admitted to hospital for heart failure. On your rounds, he asks why he is not getting better. He has a history of heart failure, hypertension, and type 2 diabetes. He has an implantable cardioverter-defibrillator. This is his fourth admission in the past 6 months for acute decompensation of his heart failure. Between hospital admissions, he reports worsening shortness of breath and a progressive decline in function. Which one of the following is the next best step?

A.

Explain the end-stage nature of the patient's illness

B.

Advise the patient to have his defibrillator deactivated

C.

Reassure the patient that his condition will improve with proper medication adherence

A 26-year-old man presents to the office with a tender mass in his right neck. He was recently treated for a dental infection but is otherwise well. On examination, there is a 2-cm tender, mobile lymph node in the right anterior cervical chain. No other lymphadenopathy or abnormalities are found on physical examination. Which one of the following is the best next step?

A.

Follow-up in 8 weeks

B.

Lymph node biopsy

C.

Computed tomography of the neck

D.

Bone marrow biopsy

E.

Ultrasonography of the spleen

You are asked to see a 50-year-old man 2 hours after he underwent a laparotomy for gastric resection. Lab results are as follows:

pH

7.28 (7.35–7.45)

PaCO₂

60 mm Hg (35–40)

PaO₂

60 mm Hg (85–105) with 4 L/min via nasal prongs

Bicarbonate (HCO₃)

24 mmol/L (24–30)

Which one of the following is most consistent with this clinical presentation?

A.

Normal recovery from an inhalation anesthetic

B.

Respiratory insufficiency

C.

Metabolic acidosis

D.

Compensatory respiratory alkalosis

E.

Postoperative hypermetabolic period

A 91-year-old man comes to the Emergency Department reporting blood in his stools, which has now resolved. He is able to give a history and mentions that this also happened 2 years ago. At that time, a colonoscopy was done and revealed diverticular disease as the cause. Which one of the following is the best next step?

A.

Perform a computed tomography colonoscopy.

B.

Order a fecal immunochemical test (FIT).

C.

Reassure him that a colonoscopy does not need to be repeated.

D.

Recommend a surgical resection of the diverticular disease.

E.

Discuss the issue with his family before making a decision.

A 35-year-old woman, gravida 3, para 0, aborta 3, presents with her male partner because she has been unable to conceive despite trying for more than 1 year. Her menstrual cycles have been absent for 9 months, and she has occasional mild cyclic pain. She has a medical history of 3 suction curettages. Her BMI is 24. Investigation results are as follows:

Hysterosalpingogram: Obliterated uterine cavity, no tubal dye spill

Progesterone (midluteal): 48.0 nmol/L (16.4–59.0)

Partner's semen: All parameters normal

Which one of the following is the most likely diagnosis?

A.

Fibroids

B.

Perimenopause

C.

Intrauterine synechiae

D.

Hypothalamic insufficiency

E.

Polycystic ovary syndrome

A 78-year-old woman is brought to the Emergency Department by her son because she has a sodium level of 124 mmol/L (136–146). The sodium was checked as part of a blood work panel ordered by her primary health care provider to investigate symptoms of urinary frequency, fatigue, and thirst. Today, she has a blood glucose level of 44.0 mmol/L (4.0–11.0). The original blood work done by her primary health care provider did not include glucose. The patient is treated for hyperglycemia and dehydration and begins insulin. The patient and her son repeatedly express their frustration that their primary health care provider missed the diagnosis. Which one of the following is the best next step?

A.

Call the primary health care provider to alert them to their oversight

B.

Report the primary health care provider to the provincial or territorial medical regulatory authority

C.

Offer to find an alternate health care provider to assume the patient’s primary care

D.

Empathize with the patient and her son and agree that the health care provider did not meet the standard of care

E.

Explain that routine glucose screening was not indicated

A 22-year-old woman presents to the office for episodic mood changes that her boyfriend has noticed. During such episodes, she cries suddenly, is irritable and sad, and withdraws from socializing. Which one of the following would be most useful in establishing a diagnosis?

A.

Personality testing.

B.

Urine drug screen.

C.

Mood journal.

D.

Trial of lorazepam.

E.

Interviewing the boyfriend alone.

A 3-week-old boy is brought by his parents to your clinic for a well-child visit. The newborn was born at term after an uncomplicated pregnancy. He is exclusively breastfed and is thriving. Physical examination findings are normal except for jaundice. Total bilirubin is 172 μmol/L (≤100), and conjugated bilirubin is 4 μmol/L (≥5). Results of a complete blood count and reticulocyte count are within the normal range. The results of a direct antiglobulin (Coombs) test were negative. Which one of the following, if any, is the most appropriate investigation?

A.

Liver enzymes and serum albumin.

B.

Hepatobiliary ultrasonography.

C.

Urine culture.

D.

Test for galactosemia.

E.

No investigation required.

A 14-month-old boy is brought to see you for a well-baby check-up and is noted to have onlyone testis. Ultrasound confirms an undescended testis. Which one of the following is the best next step?

A.

Observation for a year

B.

Surgical orchiopexy

C.

Hormonal therapy with testosterone

D.

Hormonal therapy with gonadotropins

E.

Surgical removal of the undescended testis

A 40-year-old woman presents to the Emergency Department with confusion and fever (38.5°C). She has a history of hypothyroidism managed with levothyroxine. Key findings include:

Blood pressure

114/78 mm Hg

Heart rate

85/min

Temperature

38.5°C

Hemoglobin

90 g/L123-157 g/L

Platelet count

25 × 10⁹/L130-400 × 10⁹/L

Peripheral blood film

Schistocytes present

Creatinine

200 μmol/L50-90 μmol/L

A.

Cirrhosis

B.

Acute myelogenous leukemia

C.

Human immunodeficiency virus

D.

Idiopathic thrombocytopenic purpura

E.

Thrombotic thrombocytopenic purpura

A 2-month-old infant is brought by his parents to your clinic with concerns regarding his frequent crying spells. He has been crying for more than 3 hours daily for many weeks. The infant has reached all age-specific developmental milestones. Which one of the following is the most important to share with the parents regarding this situation?

A.

This is a self-limited condition

B.

Resolution of the crying spells is expected between ages 6 and 12 months

C.

Investigations are required to confirm a diagnosis

D.

Most infants respond well to low-dose sedative medications

E.

There is an increased risk for dependent personality traits in adulthood

An 88-year-old married man is admitted following a cardiac arrest at home. He was not expected to recover, and after 2 weeks, he remains in a coma. His wife states, "I cannot let him go. That would be murder." As the attending physician looking after her husband, which one of the following is the best next course of action?

A.

Say nothing further and wait until she comes around to accepting his state

B.

Remove him from life support as this would not be murder

C.

Emphasize that the duration of his stay in the Intensive Care Unit will be limited

D.

Encourage her to imagine what her husband would have wanted

E.

Seek advice from the provincial or territorial public guardian

A 42-year-old man presents with a history of fatigue and weight loss. He looks unwell, has a darker than usual complexion and his liver is enlarged. He is also found to have marked glycosuria. Which one of the following is the most useful diagnostic test?

A.

Hemoglobin A1c

B.

Serum cortisol

C.

Serum alpha-1 antitrypsin

D.

Serum ferritin

E.

Serum amylase

A 64-year-old man presents with a 3-month history of gradually increasing neck pain and stiffness. The pain radiates into his upper back, and he is having difficulty driving because of limitation of neck rotation secondary to pain. Physical examination shows restricted neck motion in all directions and neck muscle spasms. There is no abnormality on neurologic examination. A radiograph shows narrowing of all of the cervical disc spaces with prominent osteophytes. Which one of the following is the most appropriate next step?

A.

Computed tomography of neck.

B.

Magnetic resonance imaging of the neck.

C.

Electromyography of upper limbs.

D.

Lumbar puncture.

E.

No further investigation.

A 70-year-old woman consults you for progressive vision problems. She describes seeing haloes at night around street lights and having double vision. Her near vision has improved. Which one of the following is an ophthalmologic examination most likely to uncover?

A.

Arcus senilis.

B.

Kayser-Fleischer ring.

C.

Altered red reflex.

D.

Retinal exudates.

E.

Increased intra-ocular pressure.

A 22-year-old woman, gravida 1, para 0, aborta 0, comes to the office at 10 weeks' gestation for her first prenatal visit. When you ask how she is doing, she becomes tearful and says she has had severe nausea and vomiting. She is not taking her prenatal vitamins regularly and feels very guilty about it. She is worried that she is harming the fetus. Which one of the following is the most appropriate management of this patient's case?

A.

Advise her to replace her vitamin with folic acid only until her nausea improves

B.

Refer her for counselling to manage her feelings of guilt

C.

Tell her she should continue to take her prenatal vitamins daily regardless of nausea

D.

Suggest that she take cannabinoids 30 minutes before taking her prenatal vitamins

E.

Prescribe ginger tablets to be taken 4 times daily

A 61-year-old man presents to the office for follow-up of recent laboratory test results. He has hypertension for which he takes amlodipine daily. His blood pressure is 148/94 mm Hg. His creatinine level is 140 µmol/L (normal 70–120), and his urine protein-to-creatinine ratio is persistently elevated. You would like to prescribe ramipril, but he refuses to take any additional medication. Which one of the following is the best next step?

A.

Determine why the patient is refusing to take more medication.

B.

Explain to the patient the importance of preventing the progression of his chronic kidney disease.

C.

Inform the patient that he eventually may need dialysis if he refuses the medication.

D.

Agree to stop the patient’s amlodipine if he takes ramipril.

E.

Provide the patient with free samples of ramipril.

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Total 230 questions
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