MCCQE Medical Council of Canada Qualifying Examination Part 1 Exam Free Practice Exam Questions (2026 Updated)

This 6-month-old presents with signs of systemic illness, tachypnea, hypoxia, and focal lung findings. In this age group, pneumonia can rapidly progress, and given the severity of symptoms, oral treatment is insufficient. Intravenous antibiotics are urgently indicated.

Toronto Notes 2023 – Pediatrics, Respiratory Infections in Infants:

“Infants under 6 months with signs of systemic illness, hypoxia (SpO2 < 94%), and respiratory distress should receive IV antibiotics. Delayed treatment may result in rapid clinical deterioration.”

MCCQE1 Objectives – Pediatrics > Respiratory Conditions:

“Candidates must recognize signs of serious lower respiratory tract infection in infants and initiate prompt IV antibiotic therapy when criteria for hospitalization are met.”

Oral antibiotics (C) are appropriate for mild outpatient pneumonia. Reassurance (B) and oral steroids (A) are inappropriate. IV fluids (D) may be supportive but do not address the infectious cause.

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Primary herpetic gingivostomatitis caused by HSV-1 is common in toddlers. It presents with high fever, irritability, drooling, refusal to eat, and painful oral ulcers on the lips, gums, and tongue. Cervical lymphadenopathy is common.

Toronto Notes 2023 – Pediatrics, “Infectious Conditions in Children”:

“Primary HSV-1 infection in children presents with high fever, cervical lymphadenopathy, and painful oral ulcers (gingivostomatitis).”

MCCQE1 Objectives (Pediatrics > 75-2: Infectious Diseases):

“Candidates must recognize viral exanthems and enanthems, including herpetic gingivostomatitis, based on clinical findings.”

Kawasaki (A) includes conjunctivitis, strawberry tongue, and extremity changes. Epiglottitis (B) presents with drooling but without oral ulcers. Mono (C) lacks the ulcerative pattern. Hand-foot-mouth (D) affects palms and soles, not inner lips and gums predominantly.

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This case features hallmark traits of antisocial personality disorder: disregard for social norms, criminal behavior, lack of remorse, impulsivity, and a history of conduct disorder (suggested by childhood ADHD and likely early behavioral problems).

Toronto Notes 2023 – Psychiatry, Personality Disorders:

“Antisocial personality disorder is characterized by disregard for rights of others, impulsivity, deceitfulness, lack of remorse, and criminal activity beginning in adolescence.”

MCCQE1 Objectives – Psychiatry > Personality Disorders:

“Candidates must distinguish antisocial personality disorder by a pattern of behavior that violates the rights of others, with evidence of conduct disorder before age 15.”

Other options do not explain the full behavioral pattern, especially the criminality and lack of remorse.

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Low HDL is best managed with lifestyle changes such as increased aerobic physical activity, smoking cessation, and weight loss. Vigorous exercise has the strongest evidence for raising HDL levels.

Toronto Notes 2023 – Cardiology, Dyslipidemia:

“Increasing physical activity is among the most effective ways to raise HDL cholesterol. There is no consistent benefit to supplements such as garlic, nor does reducing salt or caffeine meaningfully raise HDL.”

MCCQE1 Objectives – Population Health > Cardiovascular Risk Management:

“Candidates should recommend evidence-based lifestyle interventions such as exercise to improve lipid profiles, particularly to increase HDL.”

Alcohol cessation (C) is generally beneficial for overall health but may actually lower HDL slightly. Garlic (D) and caffeine (E) are not evidence-based interventions for dyslipidemia.

This adolescent exhibited acute suicidal behavior (attempted to jump out of a window), which is a psychiatric emergency. Regardless of intoxication or cause, such behavior mandates a safety-first approach: involuntary psychiatric assessment and protection from self-harm.

Toronto Notes 2023 – Psychiatry, “Suicide and Crisis Intervention” Section:

“Involuntary psychiatric admission is indicated when a patient poses a danger to themselves or others. Suicidal ideation or attempts require immediate evaluation and monitoring.”

MCCQE1 Objectives (Psychiatry > 79-2: Suicide and Risk Management):

“Candidates must identify suicidal behavior and initiate appropriate action, including involuntary admission if necessary for safety.”

Observation (B) may miss the window for action. Parents (A) should be contacted but are not a substitute for admission. Chlordiazepoxide (C) is not first-line in this scenario.

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In a patient with known diverticular bleeding and no red flags (e.g., weight loss, anemia, family history), repeating colonoscopy is not required. Diverticular bleeding is typically self-limited. Colonoscopy within the past few years with clear findings suffices.

Toronto Notes 2023 – Gastroenterology, Lower GI Bleed:

“Patients with known diverticulosis and self-limited bleeding who have had prior complete colonoscopy do not require repeat endoscopy unless symptoms recur or persist.”

MCCQE1 Objectives – Internal Medicine > Gastroenterology:

“Candidates must recognize when no further invasive investigation is necessary in elderly patients with known benign findings and resolved symptoms.”

Option E is considerate but not clinically necessary for independent patients. Options A, B, and D are not indicated in resolved, low-risk cases.

MCCQE ELOM objectives stress that physicians must prescribe controlled substances responsibly, use evidence-based pain management, and maintain professional boundaries despite pressure or threats of complaints. A threat to complain does not obligate opioid prescribing, especially in a patient with opioid use disorder where opioids increase risk of relapse, overdose, and diversion. The appropriate response is to remain calm, document the assessment and rationale, and ensure the patient is offered safe alternatives and continuity of care. Directing him to his methadone maintenance program is best because it supports coordinated management within an established addiction-treatment framework (often with structured monitoring, agreements, and access to addiction/pain expertise).

Prescribing “a small amount” or giving an injection undermines safe prescribing practices and reinforces drug-seeking behavior. Calling police is reserved for immediate safety threats, not dissatisfaction. Lumbar radiography is not the next step unless red flags are present; it does not address the ethical issue. Coordinated care with the methadone program and non-opioid strategies is the safest, most appropriate action.

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This infant has persistent vomiting with feeding-associated distress and poor weight gain, despite appropriate initial nonpharmacologic measures (thickened feeds and hypoallergenic formula). MCCQE pediatrics objectives emphasize distinguishing physiologic reflux (“happy spitter”) from gastroesophageal reflux disease (GERD), which is suggested by feeding aversion/crying and failure to thrive. When conservative strategies fail and GERD is causing significant symptoms or complications (e.g., poor growth, suspected esophagitis contributing to irritability and possibly anemia), escalation to acid suppression is appropriate; a proton pump inhibitor such as omeprazole is used to treat acid-related esophageal injury and improve symptoms in selected infants with suspected erosive disease.

Metoclopramide is not preferred due to limited benefit and risk of extrapyramidal adverse effects. Calcium carbonate antacids are not recommended as ongoing therapy in infants due to safety concerns and inferior efficacy for esophagitis. Bismuth sulfate is not indicated. Loperamide is inappropriate and potentially harmful in infants. Continued monitoring of growth and reassessment for alternative diagnoses or alarm features is essential.

This presentation best fits osteomyelitis, likely subacute given the 2-week course and radiographic metaphyseal sclerosis. MCCQE objectives stress that fever, systemic malaise, and elevated inflammatory markers (CRP above normal) with localized limb pain/limp should prompt consideration of bone infection even if the child can still weight-bear. Osteomyelitis in children commonly involves the metaphysis of long bones due to vascular anatomy; early x-rays may be normal, but with time they can show periosteal reaction or sclerosis. In contrast, transient synovitis typically occurs after a viral illness, is usually afebrile or minimally febrile, and inflammatory markers are often normal. Legg-Calvé-Perthes is classically age 4–8 and affects the femoral epiphysis/head with avascular necrosis changes rather than metaphyseal sclerosis and systemic illness. SCFE presents in adolescents with limp and limited internal rotation/obligate external rotation, usually without fever or elevated CRP, and x-ray shows epiphyseal slip. An undisplaced fracture would usually have trauma history and not systemic features.

Comprehensive and Detailed Explanation:

Hyponatremia in a patient with lung cancer and euvolemia strongly suggests syndrome of inappropriate antidiuretic hormone secretion (SIADH), especially from small cell carcinoma. Serum osmolality is the best initial test to confirm hypotonic hyponatremia and distinguish true hyponatremia from pseudohyponatremia or other causes.

Toronto Notes 2023 – Endocrinology, “Hyponatremia”:

“Serum osmolality helps classify hyponatremia as hypotonic, isotonic, or hypertonic. SIADH typically causes hypotonic hyponatremia in euvolemic patients.”

MCCQE1 Objectives (Endocrinology > 37-1: Electrolyte Disorders):

“Candidates must evaluate the type and cause of hyponatremia using clinical status and laboratory tests including serum osmolality.”

Urine sodium (B) is useful after confirming hypotonicity. PTHrP (E) is associated with hypercalcemia of malignancy, not hyponatremia. Urinalysis (A) and CrCl (D) are less directly informative.

The patient has clinical evidence of genital warts (condyloma acuminata), which are caused by low-risk HPV types. Even though she is not currently sexually active and has visible warts, HPV vaccination is still beneficial for protection against other oncogenic strains (especially types 16 and 18). Vaccination is safe and recommended up to age 45.

Toronto Notes 2023 – Gynecology, " STIs and HPV " :

“Vaccination is recommended up to age 45, regardless of prior exposure or visible warts. It may prevent reinfection with or acquisition of high-risk HPV strains.”

MCCQE1 Objectives (Gynecology > 83-3: STIs and HPV):

“Candidates must counsel patients appropriately on prevention, including the role of HPV vaccination, even after exposure or infection.”

Pap testing (B) is routine screening, not management of visible warts. Cryotherapy (D) is optional if the patient desires removal, but she declined treatment. Biopsy (A) is reserved for atypical lesions. Contact tracing (E) is not typically required for HPV warts.

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Comprehensive and Detailed Explanation:

This neonate likely has gonococcal conjunctivitis, which typically presents 2–5 days after birth with bilateral purulent discharge and swelling. This is an emergency due to the risk of corneal perforation. Empiric IV antibiotics and hospital admission are indicated.

Toronto Notes 2023 – Pediatrics, Neonatal Infections:

“Neonatal conjunctivitis within the first 1–2 weeks should raise suspicion for gonococcal or chlamydial infection. Gonorrhea requires urgent IV antibiotics and hospitalization.”

MCCQE1 Objectives – Pediatrics > Neonatal Infection:

“Candidates must recognize neonatal conjunctivitis and initiate empiric treatment while awaiting culture results.”

Lacrimal massage (E) and warm compresses (D) are used for nasolacrimal duct obstruction. Oral or topical antibiotics (B, C) are insufficient for suspected gonococcal infection.

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Chlamydia trachomatis is the most common cause of cervicitis in young sexually active women and frequently presents with dysuria, dyspareunia, intermenstrual bleeding, and a normal vulvovaginal exam. It may be asymptomatic or have subtle signs and often affects the endocervix.

Toronto Notes 2023 – Gynecology, “Sexually Transmitted Infections” Section:

“Chlamydia is the most common bacterial STI. Symptoms may include intermenstrual bleeding, postcoital bleeding, dyspareunia, mucopurulent cervical discharge, and dysuria. The vulva and vagina may appear normal.”

MCCQE1 Objectives (Obstetrics and Gynecology > 82-1: Abnormal Uterine Bleeding):

“Candidates should evaluate STI-related cervicitis as a common cause of postcoital and intermenstrual bleeding in young women.”

Other options:

A. Actinomyces israelii is associated with IUD use, not relevant here.

B. Herpes simplex virus usually presents with painful ulcerations, not abnormal bleeding.

C. Treponema pallidum (syphilis) causes painless ulcers or systemic symptoms in later stages.

D. HPV causes warts or asymptomatic cervical dysplasia, not acute symptoms.

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This presentation is classic for Zenker diverticulum, characterized by progressive dysphagia, regurgitation of undigested food, coughing, and halitosis due to food retention in a pharyngoesophageal pouch. Symptoms are chronic and episodic, often involving regurgitation hours after eating. MCCQE objectives emphasize selecting the safest and most appropriate diagnostic test. The best initial test is a barium swallow (contrast esophagram), which clearly visualizes the posterior outpouching above the upper esophageal sphincter.

Endoscopy is not the first step because there is a risk of perforation if a large diverticulum is present. pH monitoring and PPI trials are used for gastroesophageal reflux disease, which does not explain regurgitation of undigested food and halitosis. CT chest is unnecessary for diagnosis.

Therefore, a barium swallow is the safest and most informative investigation to confirm suspected Zenker diverticulum before considering surgical or endoscopic management.

This ABG reveals primary respiratory acidosis (↓pH, ↑PaCO₂, normal HCO₃), likely from hypoventilation due to postoperative pain, sedation, or narcotics. PaO₂ is also low, suggesting inadequate oxygenation.

Toronto Notes 2023 – Respiratory, “Postoperative Respiratory Complications”:

“Postoperative respiratory acidosis results from hypoventilation, often due to pain, sedatives, or poor respiratory effort. Assess airway, breathing, and support oxygenation.”

MCCQE1 Objectives (Internal Medicine > 44-3: Acid-Base Disturbances):

“Candidates must recognize respiratory acidosis on ABG and relate findings to common postoperative complications.”

Metabolic acidosis (C) would show ↓HCO₃. Compensated alkalosis (D) would show opposite ABG changes. Hypermetabolic states increase respiratory drive, not decrease it.

This patient has a family history of both male breast cancer (father) and early-onset ovarian cancer (aunt), which are red flags for BRCA1/2 mutations. Genetic counseling and BRCA testing are the appropriate next steps to stratify cancer risk and guide screening and prevention.

Toronto Notes 2023 – Oncology, “Breast Cancer Risk” Section:

“BRCA testing is recommended for individuals with a strong family history of breast or ovarian cancer, particularly if involving male relatives or early-onset cases.”

MCCQE1 Objectives (Population Health > 97-5: Screening and Prevention):

“Candidates must identify high-risk individuals who require genetic counseling and screening beyond population guidelines.”

Tamoxifen (A) and prophylactic mastectomy (E) are only considered after confirming mutation status. Annual screening starting at 50 (D) is for average-risk women. Fine-needle sampling (C) is not a screening tool.

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Comprehensive and Detailed Explanation:

Decreased libido in elderly patients can be multifactorial, but depression is a common and important cause that must be ruled out before hormone therapy or other steps. A proper mental health screen should precede further interventions.

Toronto Notes 2023 – Psychiatry / Geriatrics:

“In elderly men, reduced libido may be linked to depression, medical illness, or medications. Depression screening is essential.”

MCCQE1 Objectives (Psychiatry > 71-1: Mood Disorders / Sexual Health):

“Candidates must consider depression as a common cause of decreased libido and assess accordingly before initiating hormone therapy.”

Testosterone testing (D) may follow. Prescribing (C) is premature. Couples counselling (B) may help if interpersonal issues are identified. Interviewing together (A) may inhibit disclosure.

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MCCQE ELOM objectives emphasize patient safety, appropriate delegation, and respecting professional scope of practice. If a nurse states an activity is outside their scope (or they are not authorized/competent in that setting), the physician should not pressure or coerce them to perform it. Delegation requires that the delegated act is permitted by regulation and workplace policy, that the person has the competence to perform it, and that appropriate supports/medical directives exist. Supervision alone does not make an out-of-scope act acceptable, so offering to “be present” does not address the underlying legal/professional boundary. Escalating immediately to the regulator is inappropriate without first clarifying the issue locally, and simply “refraining from asking again” fails to ensure the infant receives indicated care today.

The best immediate step is to ensure timely care by administering the immunizations yourself. Afterward, discuss the matter with the nurse to clarify clinic policy, required medical directives, training/competency, and how immunizations should be handled in this practice going forward (e.g., establishing protocols so authorized staff can provide vaccines safely).