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FPGEE NABP Foreign Pharmacy Graduate Equivalency Examination Free Practice Exam Questions (2025 Updated)

Prepare effectively for your NABP FPGEE Foreign Pharmacy Graduate Equivalency Examination certification with our extensive collection of free, high-quality practice questions. Each question is designed to mirror the actual exam format and objectives, complete with comprehensive answers and detailed explanations. Our materials are regularly updated for 2025, ensuring you have the most current resources to build confidence and succeed on your first attempt.

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Total 426 questions

Mechanism of action of amiloride is:

A.

Inhibits dihydrofolate reductase

B.

Modulation of CD3 receptor from the cell surface

C.

Inhibits renal epithelial Na channels

D.

Aldosterone antagonist

E.

Inhibits DNA-dependent RNA polymerase

Route of administration of interferon alpha is:

A.

Intramuscular

B.

Inhalation

C.

Topical

D.

Oral

E.

Intra-auricular

Interactions with other drugs of tramadol is?

A.

beta-lactam antibiotics - synergism

B.

Rifampin: stimulates metabolism

C.

Phenytoin: stimulates metabolism

D.

MAO inhibitors: increase hyperpyrexia, excitation, delirium, seizures.

E.

Antihistamines: enhance analgesia

Which Cytochrome P450 isozyme does not participate appreciably in drug metabolism?

A.

CYP1A2

B.

CYP2C9

C.

CYP3A4

D.

CYP51

E.

All are drug metabolizing isoforms

In a zero order elimination process, which of the following is true?

A.

The removal of drug is independent of drug concentration

B.

Cl = Elimination rate/Cp

C.

t1/2 = .7VD/Cl

D.

All are true

dication of ciprofloxacin is:

A.

In Tuberculosis

B.

Migraine prophylaxis

C.

Tricyclic antidepressant poisoning

D.

Broad spectrum antibacterial agent

E.

Asthma

Half-life of adenosine is:

A.

70 days

B.

7-20 hours

C.

4 hours

D.

2 hours

E.

1-2 minutes

Which of the following are similarities between Cytochrome P450 and MAO?

A.

Both add oxygen from O2 to substrates and also form water

B.

Both carry out direct heteroatom oxidations

C.

Both carry out oxidative deaminations

D.

Both carry out N-dealkylations

E.

All of the above

Which of the following statements refers to bretylium?

A.

May induce mild hypotension and worsen congestive heart failure in some patients. However, most CHF patients can tolerate it.

B.

Duration of action is usually several days.

C.

Has been show to be more effective than six other agents in preventing arrhythmia recurrence and death in patients with ventricular tachyarrhythmias.

D.

Is effective against erythrocytic forms.

E.

Used in emergency setting during attempted resuscitation when lidocaine and cardioversion have failed.

Class of buspirone is:

A.

Anticonvulsants

B.

Lipid lowering drugs

C.

Beta blockers

D.

Benzodiazepines

E.

Sedatives

A drug ending in the suffix (pril) is considered a ______.

A.

H2 agonist

B.

ACE inhibitor

C.

Antifungal

D.

Beta agonist

Which of the following drugs is associated with the reaction of Cinchonism?

A.

Valproic acid

B.

Quinidine

C.

Isoniazid

D.

Ethosuximide

Which of the following statements best describes the action of the antitubercular agent ISONIAZID?

A.

Inhibit cell wall synthesis of mycobacterium

B.

Inhibit the DNA duplication of mycobacterium

C.

Inhibit arachydonic acids that feed mycobacterium

D.

Inhibit mycolic acids that are unique for mycobacterium

E.

Inhibit protein synthesis of mycobacterium

Correct statements regarding antibiotics may include:

A.

Drugs derivated from synthetic substances that can kill or inhibit bacterial growth

B.

Drugs derivated from natural source that can kill or inhibit bacteria growth

C.

Drug with ability only to kill bacteria

D.

Drug with ability only to inhibit bacterial growth

E.

All are wrong regarding antibiotics

Penicillin should be administrated 1 hour before meals or 2 to 3 hours after meals in order to:

I- Improve the bioavailability

II- Maximize the dissolution rate

III- Avoid interaction with calcium ions

A.

I only

B.

III only

C.

I and II only

D.

II and III only

E.

All are correct

Wrong statement regarding MACROLIDES ANTIBIOTICS include:

A.

Used in both gram-positive and gram-negative infections

B.

Used as an alternative to penicillin when patient has allergy to penicillins

C.

Inhibit cell wall synthesis of microorganisms

D.

Increase gastric motility causing cramps and diarrhea as major side effect

E.

Very safe for children

Class of pectin is:

A.

Analgesics

B.

Glucocorticosteroids

C.

Methylxanthines

D.

Antidiarrheal agents

E.

Antiarrhythmic agents

Class of bethanecol is:

A.

NSAID

B.

Autonomic nervous system drugs

C.

Antiarrhythmic agents

D.

Inotropic agents

E.

Beta blockers

Subclass of norfloxacin is:

A.

III

B.

Fluoroquinolones

C.

IC

D.

Bulk-forming laxatives

E.

II

Wrong statement regarding antifungal agents includes which of the following?

A.

Polyene antifungal act binding to ergosterol from pores resulting in linkage of cellular.

B.

Azoles antifungal act blocking the synthesis of ergosterol.

C.

Polyene antifungal has the widest spectrum compared to any other agent

D.

Side effects of antifungals include fever, chills, anorexia, headaches and muscle pain

E.

Side effects of antifungals cannot be treat for Tylenol due to high drug interaction.

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Total 426 questions
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